Laurence Duplomb Selected Research

Cohen syndrome

1/2019	Serpin B1 defect and increased apoptosis of neutrophils in Cohen syndrome neutropenia.
12/2015	Insulin response dysregulation explains abnormal fat storage and increased risk of diabetes mellitus type 2 in Cohen Syndrome.
5/2014	Cohen syndrome is associated with major glycosylation defects.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Laurence Duplomb Research Topics

Disease

8	Neoplasms (Cancer) 01/2020 - 09/2002
3	Cohen syndrome 01/2019 - 05/2014
2	Intellectual Disability (Idiocy) 01/2020 - 01/2016
2	Neurodevelopmental Disorders 01/2020 - 01/2016
2	Type 2 Diabetes Mellitus (MODY) 12/2015 - 01/2004
2	Bone Resorption 01/2011 - 04/2010
2	Osteosarcoma (Osteogenic Sarcoma) 05/2009 - 11/2008
2	Hyperlipidemias (Hyperlipidemia) 05/2004 - 01/2004
1	Cataract (Cataracts) 01/2020
1	Brain Diseases (Brain Disorder) 01/2020
1	Infections 01/2019
1	Neutropenia 01/2019
1	Microsatellite Instability 07/2016
1	Colorectal Neoplasms (Colorectal Cancer) 07/2016
1	Insulin Resistance 12/2015
1	Diabetes Mellitus 12/2015
1	Carcinogenesis 07/2015
1	Ataxia (Dyssynergia) 06/2012
1	Hypercalcemia (Milk Alkali Syndrome) 04/2010
1	Hyperthyroidism 10/2004
1	Fibrosis (Cirrhosis) 09/2004
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 09/2004
1	Cardiomyopathies (Cardiomyopathy) 09/2004
1	Hyperglycemia 01/2004
1	Obesity 01/2004

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 01/2016 - 11/2009
3	CytokinesIBA 05/2009 - 09/2002
2	Messenger RNA (mRNA)IBA 01/2011 - 01/2004
2	Complementary DNA (cDNA)IBA 09/2004 - 05/2004
1	Fragile X Mental Retardation ProteinIBA 01/2020
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020
1	Deubiquitinating EnzymesIBA 01/2020
1	ChromatinIBA 01/2020
1	Retinaldehyde (Retinal)IBA 01/2020
1	SerpinsIBA 01/2019
1	Biological ProductsIBA 01/2019
1	Small Interfering RNA (siRNA)IBA 07/2016
1	Semaphorins (Semaphorin)IBA 01/2016
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 12/2015
1	Insulin (Novolin)FDA Link 12/2015
1	Membrane Proteins (Integral Membrane Proteins)IBA 05/2014
1	DNA (Deoxyribonucleic Acid)IBA 06/2012
1	GlycosaminoglycansIBA 01/2011
1	Heparin (Liquaemin)FDA LinkGeneric 01/2011
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2011
1	GalliumIBA 04/2010
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2009
1	LigandsIBA 11/2009
1	Interleukin-6 (Interleukin 6)IBA 05/2009
1	Oncostatin MIBA 05/2009
1	Cytostatic AgentsIBA 05/2009
1	Conditioned Culture MediaIBA 11/2008
1	Thyroid HormonesIBA 10/2004
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2004
1	LeptinIBA 09/2004
1	LipidsIBA 09/2004
1	Acyl Coenzyme A (Acyl CoA)IBA 09/2004
1	Triglycerides (Triacylglycerol)IBA 05/2004
1	beta-Galactosidase (Lactaid)IBA 05/2004
1	EnzymesIBA 01/2004
1	GlucocorticoidsIBA 01/2004
1	Troglitazone (Rezulin)FDA Link 01/2004
1	Cytokine Receptors (Cytokine Receptor)IBA 09/2002

Therapy/Procedure

1	Lenses 01/2020
1	Drug Therapy (Chemotherapy) 07/2016